KATHMANDU — A new study by Emory University researchers have found that the fatal Zika virus can infect and replicate in immune cells from the placenta, without killing them.
According to the researchers, little was known about how the virus was replicating in placenta and in what cell type.
The finding showed that Zika virus could infect Hofbauer cells — placental macrophages — in cell culture.
Hofbauer cells are foetally derived, in contrast with other immune cells found in the placenta called decidual macrophages, which are maternally derived.
They are thought to be more tolerant and less prone to inflammatory responses than other immune cells, the researchers said.
However, signs of antiviral and inflammatory responses were detected in infected Hofbauer cells.
The study, published in the journal Cell Host & Microbe, may explain how the virus can pass through the placenta of a pregnant woman, on its way to infect developing brain cells in her foetus.
With Agency inputs
PM congratulates Nepali national cricket team
KATHMANDU— Prime Minister KP Sharma Oli has congratulated Nepali national cricket team for being able to clinch the International T20 series.
PM Oli in a tweet extended best wishes and congratulations saying he was very happy to know Nepal’s win over the UAE by 14 runs in the third match of the series.
Winning T20 series is another landmark success for Nepali cricket, he said, adding, “It is big achievement for Nepal’s cricket. I would like to heartily congratulate entire members of Nepali cricket squad”.