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Women with PCOS linked to child with autism

Gorkha Post

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Women with polycystic ovary syndrome (PCOS) are more likely to have an autistic child than other women, according to an analysis of NHS data carried out by a team at Cambridge University’s Autism Research Centre.

The researchers found that women with PCOS had a 2.3 percent chance of having an autistic child, compared to the 1.7 percent chance for mothers without PCOS.

Researchers studied 8,588 women in Britain with PCOS and their first-born children, comparing them to 41,127 women without PCOS from 1990 to 2014 in the research published in the journal Translational Psychiatry.

PCOS, which is caused by elevated levels of the hormone testosterone in fluid-filled sacs — called follicles — in the ovaries. Symptoms include onset of puberty, irregular menstrual cycles and excess bodily hair. It affects up to 20 percent of reproductive-age women worldwide, according to the National Institutes of Health.

Autism, which develops in childhood and continues through adulthood, is a neurological and developmental disorder.

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“We need to think about the practical steps we can put in place to support women with PCOS as they go through their pregnancies,” said Dr Carrie Allison, who co-supervised the research.

“The likelihood is statistically significant but nevertheless still small, in that most women with PCOS won’t have a child with autism, but we want to be transparent with this information,” he added.

They took into account other factors, including maternal mental health problems or complications during pregnancy.

“We need to think about the practical steps we can put in place to support women with PCOS as they go through their pregnancies,” Allison said in a press release.

With Agencies Inputs

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Sudden cardiac arrests are more likely to happen on any day at any time : Study

Raghu Kshitiz

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A new study has showed that sudden cardiac arrests are more likely to happen on any day at any time, challenging previous claims that weekday mornings — especially Mondays — were the danger zones.

Previously heart experts have long believed that weekday mornings were the danger zones for unexpected deaths from sudden cardiac arrests.

“While there are likely several reasons to explain why more cardiac arrests happen outside of previously identified peak times, stress is likely a major factor,” said Sumeet Chugh, a Professor of medicine from the Smidt Heart Institute in the US.

“We now live in a fast-paced, ‘always on’ era that causes increased psycho-social stress and possibly an increase in the likelihood of sudden cardiac arrest,” Chugh added.

Almost 17 million cardiac deaths occur annually worldwide while the survival rate from sudden cardiac arrest is less than one per cent.

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For the study, published in the journal Heart Rhythm, Chugh’s team analysed data on 1,535 from the community-based Oregon Sudden Unexpected Death Study between 2004 to 2014, among which only 13.9 per cent died in the early morning hours, the findings revealed.

All reported cases were based on emergency medical service reports containing detailed information regarding the cause of the cardiac arrest.

“Because sudden cardiac arrest is usually fatal, we have to prevent it before it strikes,” Chugh said. “Our next steps are to conclusively determine the underlying reasons behind this shift, then identify public health implications as a result,” he added.

Apart from stress, other contributing factors may be a shift in how high-risk patients are being treated, as well as inadequacies in how past studies have measured time of death caused by sudden cardiac arrest.

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