KATHMANDU — People with vitamin D deficiency might have a greater risk of developing diabetes, researchers at the University of California San Diego School of Medicine and Seoul National University said in a new study report.
For the study published in PLOS One, researchers studied 903 healthy adults without pre-diabetes or diabetes during clinic visits from 1997 to 1999, and followed up with them for 10 years, to study their levels of 25-hydroxyvitamin and their medical condition.
Among the study participants, who had a mean age of 74, researchers found 47 new cases of diabetes and 337 new cases of pre-diabetes.
“Further research is needed on whether high 25-hydroxyvitamin D levels might prevent type 2 diabetes or the transition from pre-diabetes to diabetes,” study co-author Dr. Cedric F Garland, adjunct professor in the UC San Diego School of Medicine Department of Family Medicine and Public Health, said in a press release.
“But this paper and past research indicate there is a strong association,” he said.
The 25-hydroxyvitamin D, which is known as the ‘sunshine’ vitamin because it’s produced in your skin in response to sunlight, also can be received through certain foods and supplements. The vitamin helps in growth and development of bones and teeth, and resistance against certain diseases.
The minimum healthy level of 25-hydroxyvitamin D in blood plasma was listed as 30 nanograms per milliliter, which is 10 ng/ml above the level recommended in 2010 by the Institute of Medicine, now part of The National Academies.
“We found that participants with blood levels of 25-hydroxyvitamin D that were above 30 ng/ml had one-third of the risk of diabetes and those with levels above 50 ng/ml had one-fifth of the risk of developing diabetes,” first author Dr. Sue K. Park, of the Department of Preventive Medicine at Seoul National University College of Medicine in South Korea, said.
Those below 30 ng/ml were considered vitamin D deficient and up to five times at greater risk for developing diabetes than those above 50 ng/ml.
To reach the D levels of 30 ng/ml, Garland said it would require dietary supplements of 3,000 to 5,000 international units per day, but less with moderate daily sun exposure.
The recommended average daily amount of vitamin D is 400 IU for children up to 1 year, 600 IU for ages 1 to 70 years and 800 IU for persons over 70, according to the National Institutes of Health.
Good food sources for vitamin D include egg yolk, shrimp,salmon, sardines, fortified milk, cereal, yogurt and orange juice.
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Sudden cardiac arrests are more likely to happen on any day at any time : Study
A new study has showed that sudden cardiac arrests are more likely to happen on any day at any time, challenging previous claims that weekday mornings — especially Mondays — were the danger zones.
Previously heart experts have long believed that weekday mornings were the danger zones for unexpected deaths from sudden cardiac arrests.
“While there are likely several reasons to explain why more cardiac arrests happen outside of previously identified peak times, stress is likely a major factor,” said Sumeet Chugh, a Professor of medicine from the Smidt Heart Institute in the US.
“We now live in a fast-paced, ‘always on’ era that causes increased psycho-social stress and possibly an increase in the likelihood of sudden cardiac arrest,” Chugh added.
Almost 17 million cardiac deaths occur annually worldwide while the survival rate from sudden cardiac arrest is less than one per cent.
For the study, published in the journal Heart Rhythm, Chugh’s team analysed data on 1,535 from the community-based Oregon Sudden Unexpected Death Study between 2004 to 2014, among which only 13.9 per cent died in the early morning hours, the findings revealed.
All reported cases were based on emergency medical service reports containing detailed information regarding the cause of the cardiac arrest.
“Because sudden cardiac arrest is usually fatal, we have to prevent it before it strikes,” Chugh said. “Our next steps are to conclusively determine the underlying reasons behind this shift, then identify public health implications as a result,” he added.
Apart from stress, other contributing factors may be a shift in how high-risk patients are being treated, as well as inadequacies in how past studies have measured time of death caused by sudden cardiac arrest.Follow @gorkhapost