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Researchers successfully grow human cells in sheep embryos

Raghu Kshitiz

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Researchers successfully grow human cells in sheep embryos. Represenatational image

KATHMANDU — In an incredible development that could possibly go a long way in medical practices, scientists in California are working on a way to reduce organ transplants and rejections: Growing embryos in sheep and pigs containing human patients’ cells.

In a transplant breakthrough, scientists at the University of California said they have achieved sheep embryos in which around one in every 10,000 cells was human, according to UPI report.

The researchers presented preliminary findings Saturday at the American Association for the Advancement of Science’s annual meeting in Austin, Texas.

The new finding paves way for genetically tailoring the organs to be compatible with the immune system of the patient receiving them, thus removing the possibility of rejection, the report said.

The hybrid embryos contain both human and sheep cells and were created in an early step toward growing human organs in farm animals before transplanting them into patients.

Last year, the same researchers introduced human stem cells into early pig embryos, producing embryos with about one in every 100,000 cells being human.

The experiment began with Hiro Nakauchi, from the University of Tokyo, who grew a mouse with a rat pancreas and a rat with a mouse pancreas.

When cells from the rat-grown mouse pancreas were transplanted into a diabetic mouse, they made enough insulin to cure the condition without being rejected.

Mice and rats are different types of rodents with the former having thin slightly hairy tails, while rats have thicker hairless scaly tails.

“The next step was to move into large animals,” Nakauchi said. Since this was prohibited in Japan, he moved to the Stanford University in the US.

Nakauchi’s rodent work has demonstrated that you can “grow organs in a different species and cure a disease without [suppressing the immune system],” added co-researcher Pablo Ross, Professor at from the University of California, Davis.

“We are working together to translate the technology into humans, to solve the terrible shortage of organs for transplantation. In the US, 20 people die every day because they cannot get the organs they need,” Ross explained.

With Agency Inputs

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Economy

Govt decides to award Budhi Gandaki Hydel project to Chinese firm again

Gorkha Post

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KATHMANDU — The government has decided to award contract for the construction of the 1,200-megawatt Budhigandaki hydropower project, a national pride project, to China Gezhouba Group Corporation (CGGC) once again.

A Cabinet meeting on Friday has decided to award the contract for the project to CGGCL reverting the erstwhile Sher Bahadur Deuba government’s decision to develop the 1200MW project with internal resources.

The Cabinet meeting has directed the Energy Ministry to initiate the process to award the project to the Chinese company.

Following the government decision, the Energy Ministry will now invite the Chinese company for talks and prepare a draft of the memorandum of understanding (MoU) before signing it, according to multiple sources at the ministry.

As per the Cabinet decision, the ministry has been asked to hold talks with the Gezhouba, prepare a proposal, and strike a deal to execute the $2.5 billion reservoir project.

Earlier on May 15, 2017, the Pushpa Kamal Dahal-led government had awarded the contract to construct the Budhigandaki project to CGGCL, juat nine days before he was to resign from the PM’s post.

The Dahal-led government had awarded the contract to CGGCL at a cost of Rs 260 billion as per a study carried out by a French company, Tractebel Engineering.

The agreement, however, invited controversy as the project was handed to the Chinese company without initiating a competitive bidding process.

The Budhi Gandaki hydel project has been touted as a key project to resolve the perennial power crisis in the country. The government has allocated Rs18 billion for compensation payments and operational expenses for this fiscal year.

The Gorkha and Dhading district administration offices are currently distributing compensation to owners of the land taken over by the project.

More than 8,000 households will be affected by the project, according to the latest report.

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