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Drinking more water doesn’t slow kidney disease in chronic kidney patients

Raghu Kshitiz



KATHMANDU — Drinking more water is generally advised — the common advice is to drink eight glasses per day –and has been associated with better kidney function and a reduced risk of kidney stones.

But drinking an extra four to six extra glasses of water per day won’t slow the decline of kidney functions for chronic kidney disease patients, according to a new study in Britain and Canada.

A study, published in JAMA (Journal of the American Medical Association) by researchers at LaLawson Health Research Institute in Ontario and Western University in London found that coaching patients with Chronic Kidney Disease (CKD) to drink more water does not slow down the decline of their kidney function.

“Despite widespread beliefs, little scientific data exists on the optimal amount of water to drink,” explains Dr. William Clark, Scientist at Lawson and Professor at Western’s Schulich School of Medicine & Dentistry.

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“While many claims about the benefits of increased water intake remain untested, a growing body of evidence suggests that increased water intake improves kidney function through the suppression of the antidiuretic hormone.”

Researchers studied whether increased hydration made a difference in people with kidney disease. The clinical trial was published Tuesday in the Journal of the American Medical Association.

The randomized clinical trial included 631 patients at London Health Sciences Center and several other hospitals in Ontario with stage 3 kidney disease from April 2013 to June 2017. At stage 3, patients have lost up to 70 percent of their kidney function.

Half of the participants were coached to drink more water — 1 to 1.5 liters per day, depending on sex and weight. Those in the control group were asked to maintain usual intake or not decrease it by more than one-quarter to a half-liter per day. One liter of water is about 34 fluid ounces.

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The researchers, after one year, found the increase of water consumption did not slow the loss of kidney function. They found, however, that the reduction significantly suppressed antidiuretic hormone release, particularly when the participant’s previous intake was low.

“This research indicates that for most patients with CKD, increasing fluid intake will not stop further loss of kidney function. It does allow us then to focus our efforts on other potential therapeutic options,” Clark said.

The researchers hope to conduct another study with a longer followup, according to them.

With Agency Inputs

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Regular bedtime beneficial for heart and metabolic health among older adults

Raghu Kshitiz



KATHMANDU — Sufficient sleep has been proven to help keep the body healthy and the mind sharp. But a new study on sleep patterns has suggested that a regular bedtime and wake time are just as important for heart and metabolic health among older adults too.

Researchers at Duke Health and the Duke Clinical Research Institute, in a study of 1,978 older adults, have found that people with irregular sleep patterns weighed more, had higher blood sugar, higher blood pressure, and a higher projected risk of having a heart attack or stroke within 10 years than those who slept and woke at the same times every day.

The study  was published Sept 21 in the journal Scientific Reports.

“From our study, we can’t conclude that sleep irregularity results in health risks, or whether health conditions affect sleep,” said study’s lead author Jessica Lunsford-Avery.

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“Perhaps all of these things are impacting each other.”

African-Americans had the most irregular sleep patterns compared to participants who were white, Chinese-American or Hispanic, the data showed.

Still, the data suggest tracking sleep regularity could help identify people at risk of disease, and where health disparities may impact specific groups.

Irregular sleepers were also more likely to report depression and stress than regular sleepers, both of which are tied to heart health.

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