KATHMANDU — Drinking at least three or more cups of coffee daily may reduce the risk of prostate cancer by 50 percent, a recent study on 7,000 Italian men has revealed.
A research by the Department of Epidemiology and Prevention — I.R.C.C.S. Neuromed, Italy, in collaboration with the Italian National Institute of Health and the I.R.C.C.S. Istituto Dermopatico dell’Immacolata of Rome, shows that three or more cups a day can lower prostate cancer risk.
The findings were then validated in laboratory studies which suggested that the coffee substance caffeine might have some protective effect against cancer.
“The observations on cancer cells allow us to say that the beneficial effect observed among the 7,000 participants is most likely due to caffeine, rather than to the many other substances contained in coffee,” said Maria Benedetta Donati from Institute for Research, Hospitalisation and Health Care (I.R.C.C.S.) Neuromed in Pozzilli, Italy.
The study, published in the International Journal of Cancer, sheds light in a field still hotly debated to this day — the role of coffee, and specifically caffeine, in relation to prostate cancer
A protective effect of the popular drink has already been suggested by some recent studies.
“In recent years we have seen a number of international studies on this issue. But scientific evidence has been considered insufficient to draw conclusions. Moreover, in some cases results were contradictory,” first author of the paper George Pounis from I.R.C.C.S., Neuromed said.
“Our goal, therefore, was to increase knowledge in this field and to provide a clearer view,” Pounis said.
“By analysing their coffee consumption habits and comparing them with prostate cancer cases occurred over time, we saw a net reduction of risk, 53 per cent, in those who drank more than three cups a day.”
Then the researchers tested, in particular, extracts containing caffeine or decaffeinated. Only the first ones significantly reduced cancer cells proliferation — an effect that largely disappeared with decaffeinated extracts.
The researchers believe that the Italian-style of coffee making might also contribute to the protective effect.
“We should keep in mind that the study is conducted on a central Italy population,” Licia Iacoviello from I.R.C.C.S. Neuromed noted.
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Drinking 3 cups of coffee or tea daily may keep stroke risk at bay
KATHMANDU — There have been several conflicting studies on the health benefits of drinking coffee and tea and their various varieties. But drinking up to three cups of coffee or tea in a day is safe because it reduces irregular heartbeat and stroke risk, according to a new study published in the journal JACC: Clinical Electrophysiology.
Coffee has previously been believed to worsen abnormal heart rhythms, as doctors generally discourage patients suffering from the condition. However, the results of this particular study say that a daily consumption of upto 300 mg of caffeine may be safe for arrhythmic patients.
This is because the caffeine acts as a stimulant to the central nervous system and blocks the effect of adenosine. Adenosine is a chemical which causes Atrial Fibrillation (AFib).
A single cup of coffee contains about 95 mg of caffeine. It acts as a stimulant to the central nervous system and works to block the effects of adenosine — a chemical that causes AFib.
AFib is the most common heart rhythm disorder, causes the heart to beat rapidly and skip beats, and if left untreated, can cause strokes.
“There is a public perception, often based on anecdotal experience, that caffeine is a common acute trigger for heart rhythm problems,” said lead author Peter Kistler, Director at Melbourne’s Alfred Hospital.
But, “caffeinated beverages such as coffee and tea have long-term anti-arrhythmic properties mediated by antioxidant effects and antagonism of adenosine,” he added.
A meta-analysis of 228,465 participants showed that AFib frequency decreasing by 6 per cent in regular coffee drinkers, and an analysis of 115,993 patients showed a 13 per cent reduced risk.
Another study of 103 post-heart attack patients who received an average of 353 mg of caffeine a day showed improvement in heart rate and no significant arrhythmias — or abnormal heart rhythms, that cause the heart to beat too fast, slow or unevenly.
However, in two studies, where patients drank at least 10 cups and nine cups of coffee per day, showed an increased risk for ventricular arrhythmias (VAs) – a condition in which the lower chambers of the heart (ventricles) beat very quickly.
On the other hand, patients with pre-existing heart conditions who consumed two or more energy drinks — that contains concentrated caffeine — per day reported palpitations within 24 hours.
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