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Insulin in combination with diabetes pills can cut mortality risk

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LONDON — A new study has found that in people with Type 2 diabetes, insulin when taken in combination with metformin — a cheap and common drug that helps control blood sugar levels — has the potential to reduce mortality risk and heart attacks.

“In this research we found that there was a considerable reduction in deaths and heart problems when this cheap and common drug was used in conjunction with insulin,” said lead author Craig Currie, professor at Cardiff University in Britain.

The retrospective research, published in the journal PLOS ONE, looked at people with Type 2 diabetes who were treated with insulin with or without metformin from the year 2000 onwards.

Increased dosage of insulin has been previously known to raise the risk of cancer, heart attacks and mortality. But the findings have shown that metformin can attenuate the risks associated with insulin.

However, according to researchers, there was no difference in the risk of cancer between people treated with insulin as a single therapy or in combination with metformin.

12,020 people were identified from a general practice data source, and the research team tracked them for three-and-a-half years on average, from the time they were first prescribed insulin.

“While this research indicates the potential of using these treatments together, further studies are needed to determine the risks and benefits of insulin in Type 2 diabetes and the possible benefits associated with the administration of metformin alongside insulin,” Currie concluded.

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First Roland Macaulay Cup to start on November 21

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BIRATNAGAR— The First Roland Macaulay Cup is being held in the capital on November 21-24.

To be organized by the Cricket Association of the Blind, Nepal, cricket clubs–Myagdi, Jhapa, Bardiya and Tribhuvan Army–will participate in the First Roland Macaulay Cup twenty20 cricket tournament, said Pawan Ghimire, the Central President of the Association at a press conference here.

The estimated budget is approximately Rs 750,000. The opening match will be held between Jhapa and Bardiya, said the organizer.

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