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Insulin in combination with diabetes pills can cut mortality risk

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LONDON — A new study has found that in people with Type 2 diabetes, insulin when taken in combination with metformin — a cheap and common drug that helps control blood sugar levels — has the potential to reduce mortality risk and heart attacks.

“In this research we found that there was a considerable reduction in deaths and heart problems when this cheap and common drug was used in conjunction with insulin,” said lead author Craig Currie, professor at Cardiff University in Britain.

The retrospective research, published in the journal PLOS ONE, looked at people with Type 2 diabetes who were treated with insulin with or without metformin from the year 2000 onwards.

Increased dosage of insulin has been previously known to raise the risk of cancer, heart attacks and mortality. But the findings have shown that metformin can attenuate the risks associated with insulin.

However, according to researchers, there was no difference in the risk of cancer between people treated with insulin as a single therapy or in combination with metformin.

12,020 people were identified from a general practice data source, and the research team tracked them for three-and-a-half years on average, from the time they were first prescribed insulin.

“While this research indicates the potential of using these treatments together, further studies are needed to determine the risks and benefits of insulin in Type 2 diabetes and the possible benefits associated with the administration of metformin alongside insulin,” Currie concluded.

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HOTC sees remarkable success rate on kidney transplant

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HOTC sees remarkable success rate on kidney transplant

BHAKTAPUR — Shahid Dharmabhakta National Human Organ Transplant Centre (HOTC), Bhaktapur has successfully undertaken transplant of over 400 kidneys.

Hospital’s Executive Director Dr Pukar Chandra Shrestha, at a press conference organised here on Friday, informed that the Centre has so far successfully transplanted kidneys on 404 patients.

The Centre had initiated the kidney transplant service on January 19, 2013.

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The inflow of patients has alarmingly increased at the facility with the start of additional medical services such as urology, gastro surgery, cardio therapy, stone removal surgery along with other surgeries, besides kidney transplant, said Prof Dr Rakesh Verma.

However, the patients are compelled to wait for the transplant for long due to limited building space and availability of beds.

Right now, around 400 patients are waiting their turns for kidney transplant and more than this number are waiting to avail of dialysis service.

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