Connect with us

Health

Common hypertension drugs linked to skin cancer risk

Raghu Kshitiz

Published

on

KATHMANDU — In a new study, the researchers have identified clear connection between the use of hypertension medicine and the chance of developing skin cancer.

Long term use of drugs that help lower high blood pressure may increase the risk of developing skin cancer, a recently published research from The University of Southern Denmark and the Danish Cancer Society, has claimed.

Specifically, this refers to drugs containing hydrochlorothiazide and squamous cell carcinoma. Hydrochlorothiazide — one of the most commonly used antihypertensive drugs worldwide — is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

In the study, published in the Journal of the American Association of Dermatology, the team observed nearly 80,000 participants and found a connection between hypertension and skin cancer.

The findings revealed that using medicines that contain hydrochlorothiazide increases the risk of developing squamous cell carcinoma — skin cancer that develops in the cells of the outer layer of the skin — up to seven times.

ALSO READ :  HOTC sees remarkable success rate on kidney transplant

“We knew that hydrochlorothiazide made the skin more vulnerable to damage from the sun’s UV rays, but what is new and also surprising is that long term use of this blood pressure medicine leads to such a significant increase in the risk of skin cancer,” said Anton Pottegard, associate professor at the University of Southern Denmark.

The researchers had previously demonstrated that hydrochlorothiazide can increase the risk of lip cancer.

However, one should not interrupt the treatment without consulting the doctor, Pottegard suggested, because “hydrochlorothiazide is an effective and otherwise safe treatment for most patients”.

Besides treating hypertension, hydrochlorothiazide is frequently used for the treatment of congestive heart failure, symptomatic edema, diabetes insipidus and renal tubular acidosis.

The pill is also used for the prevention of kidney stones in those who have high levels of calcium in their urine.

“Nevertheless, our results should lead to a reconsideration of the use of hydrochlorothiazide. Hopefully, with this study, we can contribute towards ensuring safer treatment of high blood pressure in the future,” Pottegard noted.

With IANS Inputs

Continue Reading

Health

Type 2 diabetes early in life found to increase risk of fatal heart disease by 60 pc

Gorkha Post

Published

on

KATHMANDU — Developing Type 2 diabetes early in life increases risk of death linked to heart disease by 60 percent, according to a study published in Diabetologia.

The condition was once considered a disease of the elderly but the obesity epidemic has led to a surge in cases in young adults and even children too.

Research on 744,000 sufferers over 15 years to 2011 found the average diagnosis age was 59 and there were 115,363 deaths during the period.

It was associated with a 60 percent higher relative risk of dying from heart disease or stroke. Not only that, it was linked to almost a 30 percent higher risk of death from any cause, though a lower risk of dying from cancer was seen.

“Type 2 diabetes in young people is somewhat aggressive and leads to higher mortality,” said study co-author Dianna Magliano, head of the diabetes and population health laboratory at the Baker Heart and Diabetes Institute in Melbourne, Australia.

ALSO READ :  EC bars 2 EU observers from poll monitoring

Dr Joel Zonszein, director of the Clinical Diabetes Center at Montefiore Medical Center in New York City, said “Type 2 diabetes has evolved through the years into a different type of disease. It used to be a disease of the elderly.” He was not involved with the study.

“What we see nowadays with Type 2 diabetes is that it’s affecting a younger population and is more aggressive. There’s more weight, more lipotoxicity, more insulin resistance and more inflammation, and inflammation can cause premature cardiovascular disease,” Zonszein said.

Lipotoxicity is when the fats in the blood, or cholesterol, build up in places they shouldn’t, such as the liver, kidneys or heart.

The researchers also think the reason the younger people had fewer cancers is that it’s just more common for older people to have cancer.

They also suggested that because this group of younger people is being treated for Type 2 diabetes, it’s possible that when they do have cancer, it’s getting diagnosed and treated sooner, because they’re already engaged in the health care system.

With Agency Inputs

Continue Reading
Advertisement Cheap Air fare and package tours!

LATEST TWEET

Classifieds

Posted 2 months ago

We have latest collections of designer sarees. Contact for wholesale or retails prices. We also deliver all types of fashion collections for men and women.

 Fashion & Clothings /  Kathmandu / 95 views

NPR 2,999.00

Posted 2 months ago

Remember us for all travel related services : Hotel booking ( Globally) Vehicle reservation Flight Ticket( Domestic/International) Tour packages Train ticket reservation Hiking and Trekking

 Travel & Tours /  Kathmandu / 86 views

NPR 2,000.00

Search Listings

TOP PICKS