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Broccoli, soybeans may cut breast cancer treatment’s side effects

Raghu Kshitiz

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NEW YORK — Consuming cruciferous vegetables (such as cabbages, kale, collard greens, bokchoy, Brussels sprouts, and broccoli) and foods (such as soy milk, tofu and edamame) might assist reduction in common side effects of breast cancer treatment in breast cancer survivors, say a team of scientists led by Georgetown Lombardi Comprehensive Cancer Center.

Higher intake of cruciferous vegetables and soy foods were associated with fewer reports of menopausal symptoms while higher soy intake was also associated with less reported fatigue.

In the study, published in Breast Cancer Research and Treatment, the breast cancer survivors included 173 non-Hispanic white and 192 Chinese Americans including US-born Chinese and Chinese immigrants.

Researchers say breast cancer survivors often experience side effects from cancer treatments that can persist months or years after completion of treatment because many treatments designed to prevent breast cancer recurrence inhibit the body’s production or use of estrogen, the hormone that can fuel breast cancer growth, breast cancer patients often experience hot flashes and night sweats, among other side effects.

While further research is needed in larger study populations and with more detailed dietary data, this project addresses an important gap in research on the possible role of lifestyle factors, such as dietary habits, in relation to side effects of treatments, said Sarah Oppeneer Nomura, PhD, of Georgetown Lombardi, the lead author on the study.

“These symptoms can adversely impact survivors’ quality of life and can lead them to stopping ongoing treatments, she says adding, “Understanding the role of life style factors is important because diet can serve as a modifiable target for possibly reducing symptoms among breast cancer survivors.”

When study participants were evaluated separately by race,ethnicity, associations were significant among white breast cancer survivors; however, while a trend was seen in the benefit for Chinese women, results were not statically significant.

Researchers explain Chinese women typically report fewer menopausal symptoms. Most of them also consume cruciferous vegetables and soy foods, making it difficult to see a significant effect in this subgroup. Indeed, in this study, Chinese breast cancer survivors ate more than twice as much soy and cruciferous vegetables.

Phytochemicals, or bioactive meals elements, reminiscent of isoflavones in soy meals and glucosinolates in cruciferous greens would be the supply of the profit, the researchers stated.

Whether the reduction in symptoms accounts for longtime use of soy and cruciferous vegetables needs further investigation, says the study’s senior author, Judy Huei-yu Wang, PhD, of Georgetown Lombardi’s Cancer Prevention and Control Program.

The research addresses an vital hole in analysis on the doable function of life-style elements, reminiscent of dietary habits, in relation to unintended effects of therapies, stated lead creator Sarah Oppeneer.

With Agency Inputs

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NC leader Regmi passes away

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KATHMANDU— Nepali Congress leader Keshab Regmi, who contributed to restoring democracy in 1990, has passed away on Thursday night.

Regmi, who was suffering from respiratory problems for long, died at his residence in Gongabu in Kathmandu. Regmi, who also served as secretary of NC, Kaski, played an important role in establishing Nepal Students’ Union, the student wing of the NC.

He was also sent to jail five times for fighting to restore democracy. He is survived by two wives.

His last rites were conducted at Pashupati Aryaghat today itself. People from various walks of life and NC leaders attended his funeral rite.

On the occasion, NC President and former Prime Minister Sher Bahadur Deuba, senior leader Ram Chandra Paudel and General Secretary Dr Shashanka Koirala paid tribute to Regmi by draping his body in the party flag.

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