WASHINGTON — Body mass index (BMI) and blood pressure are positively associated, according to a new study being conducted by researchers at the Yale Center for Outcomes Research and Evaluation (CORE) in China.
In the ongoing study of 1.7 million Chinese men and women, individuals who were not taking an antihypertensive medication, were observed with an increase of 0.8 to 1.7 mm Hg (kg/m2) in blood pressure per additional unit of BMI.
First author and doctoral candidate at Yale, George Linderman said, “The enormous size of the dataset — the result of an unprecedented effort in China — allows us to characterize this relationship between BMI and blood pressure across tens of thousands of subgroups, which simply would not be possible in a smaller study.”
Researchers recorded the participants’ blood pressure from September 2014 through June 2017 as part of the larger China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Million Persons Project, which captures at least 22,000 subgroups of people based on age (35-80), sex, race/ethnicity, geography, occupation, and other pertinent characteristics — such as whether or not they are on antihypertensive medication.
Senior author on the study Harlan Krumholz said, “If trends in overweight and obesity continue in China, the implication of our study is that hypertension, already a major risk factor, is likely to become even more important. This paper is ringing the bell that the time is now to focus on these risk factors.”
According to the researchers, one way for the Chinese healthcare system to address these risk factors would be the management of high blood pressure with antihypertensive drugs.
The full findings are present in the journal-JAMA Network Open.
Sudden cardiac arrests are more likely to happen on any day at any time : Study
A new study has showed that sudden cardiac arrests are more likely to happen on any day at any time, challenging previous claims that weekday mornings — especially Mondays — were the danger zones.
Previously heart experts have long believed that weekday mornings were the danger zones for unexpected deaths from sudden cardiac arrests.
“While there are likely several reasons to explain why more cardiac arrests happen outside of previously identified peak times, stress is likely a major factor,” said Sumeet Chugh, a Professor of medicine from the Smidt Heart Institute in the US.
“We now live in a fast-paced, ‘always on’ era that causes increased psycho-social stress and possibly an increase in the likelihood of sudden cardiac arrest,” Chugh added.
Almost 17 million cardiac deaths occur annually worldwide while the survival rate from sudden cardiac arrest is less than one per cent.
For the study, published in the journal Heart Rhythm, Chugh’s team analysed data on 1,535 from the community-based Oregon Sudden Unexpected Death Study between 2004 to 2014, among which only 13.9 per cent died in the early morning hours, the findings revealed.
All reported cases were based on emergency medical service reports containing detailed information regarding the cause of the cardiac arrest.
“Because sudden cardiac arrest is usually fatal, we have to prevent it before it strikes,” Chugh said. “Our next steps are to conclusively determine the underlying reasons behind this shift, then identify public health implications as a result,” he added.
Apart from stress, other contributing factors may be a shift in how high-risk patients are being treated, as well as inadequacies in how past studies have measured time of death caused by sudden cardiac arrest.Follow @gorkhapost