A sperm sorting device that can help infertile couples
NEW YORK — Researchers have built up a new device that can sort the best sperm out of millions in just 30 minutes for their use in assisted reproductive technologies such as in vitro fertilisation.
With this device, the couples who are looking for having a baby on their own but find it difficult to conceive will be able to fulfill their dreams of having healthier babies.
The device, based on microfluidic technology, reduces risk of DNA damage associated with conventional sperm sorting method.
Around the world, about 48.5 million couples have been been unable to have a child after trying for five years or more. While in vitro fertilization, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.
While in vitro fertilisation, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.
“DNA damage is one of the more important characteristics of sperm, because higher levels of damage are associated with lower pregnancy rates, early loss of pregnancy, and increased disease rates of offspring who are conceived through assisted reproductive technologies,” said Waseem Asghar, Assistant Professor at Florida Atlantic University in the US.
“That’s why it is so important to develop methods to select the healthiest sperm for assisted reproductive technologies,” Asghar noted.
The most commonly used or conventional method for assisted reproductive technologies involves a technique called centrifugation.
Although this method is efficient at selecting motile and morphologically normal sperm, the process is problematic because it tends to increase levels of certain chemicals that cause DNA damage.
Asghar’s device consists of one inlet for the injection of a raw unprocessed semen sample and two plastic chambers separated by porous membrane.
Compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.
The findings were presented in the journal Biotechnology Advances.Follow @gorkhapost
Nirmala Panta rape, murder case : Locals protest after wrong suspect paraded
BHIMDUTTANAGAR — Locals who were protesting against the rape and murder of Nirmala Panta of Kanchanpur’s Bhimdatta Municipality, have enforced shutdown in Bhimduttanagar Bazaar on Tuesday, protesting police’s failure to reveal facts behind the murder of 13-year-old girl and parading wrong suspect on Monday.
The District Police Office, organising a press conference on Monday,had made public Dilip Singh Bista (41), of Baghphanta, Bhimdatta Municipality-19 as Nirmala’s murderer.
Locals have shut down the market area stating that police were not being able to make public the true murderer(s) as they are not convinced by the findings of police citing that Bista was mentally unsound, according to the District Police Office.
Transportation has also been halted.
Bista, a resident of Khanna Chauraha area in Bhimdutta Municipality-19, was apprehended near the scene of crime on Sunday, according to police.
Police making public the wrong suspect has infuriated the locals and fueled the protest.
The agitators including various civil society organisations and human rights defenders have been picketing the District Administration Office and staging rally on the street mounting pressure on the police to reveal the facts behind the heinous crime.
Meanwhile, it had been learnt that police have fired rounds of teargas shells to contain the agitated mob.
Nirmala was found murdered in a sugarcane field on July 27, a day after she had gone to her friend’s home to get a notebook.Follow @gorkhapost