A sperm sorting device that can help infertile couples
NEW YORK — Researchers have built up a new device that can sort the best sperm out of millions in just 30 minutes for their use in assisted reproductive technologies such as in vitro fertilisation.
With this device, the couples who are looking for having a baby on their own but find it difficult to conceive will be able to fulfill their dreams of having healthier babies.
The device, based on microfluidic technology, reduces risk of DNA damage associated with conventional sperm sorting method.
Around the world, about 48.5 million couples have been been unable to have a child after trying for five years or more. While in vitro fertilization, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.
While in vitro fertilisation, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.
“DNA damage is one of the more important characteristics of sperm, because higher levels of damage are associated with lower pregnancy rates, early loss of pregnancy, and increased disease rates of offspring who are conceived through assisted reproductive technologies,” said Waseem Asghar, Assistant Professor at Florida Atlantic University in the US.
“That’s why it is so important to develop methods to select the healthiest sperm for assisted reproductive technologies,” Asghar noted.
The most commonly used or conventional method for assisted reproductive technologies involves a technique called centrifugation.
Although this method is efficient at selecting motile and morphologically normal sperm, the process is problematic because it tends to increase levels of certain chemicals that cause DNA damage.
Asghar’s device consists of one inlet for the injection of a raw unprocessed semen sample and two plastic chambers separated by porous membrane.
Compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.
The findings were presented in the journal Biotechnology Advances.Follow @gorkhapost
First Roland Macaulay Cup to start on November 21
BIRATNAGAR— The First Roland Macaulay Cup is being held in the capital on November 21-24.
To be organized by the Cricket Association of the Blind, Nepal, cricket clubs–Myagdi, Jhapa, Bardiya and Tribhuvan Army–will participate in the First Roland Macaulay Cup twenty20 cricket tournament, said Pawan Ghimire, the Central President of the Association at a press conference here.
The estimated budget is approximately Rs 750,000. The opening match will be held between Jhapa and Bardiya, said the organizer.Follow @gorkhapost