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A sperm sorting device that can help infertile couples

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A sperm sorting device that can help infertile couples

NEW YORK — Researchers have built up a new device that can sort the best sperm out of millions in just 30 minutes for their use in assisted reproductive technologies such as in vitro fertilisation.

With this device, the couples who are looking for having a baby on their own but find it difficult to conceive will be able to fulfill their dreams of having healthier babies.

The device, based on microfluidic technology, reduces risk of DNA damage associated with conventional sperm sorting method.

Around the world, about 48.5 million couples have been been unable to have a child after trying for five years or more. While in vitro fertilization, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.

While in vitro fertilisation, intrauterine insemination, and intracytoplasmic sperm injection have been effective treatment options for infertile couples, only about one-third of these methods result in live births.

“DNA damage is one of the more important characteristics of sperm, because higher levels of damage are associated with lower pregnancy rates, early loss of pregnancy, and increased disease rates of offspring who are conceived through assisted reproductive technologies,” said Waseem Asghar, Assistant Professor at Florida Atlantic University in the US.

“That’s why it is so important to develop methods to select the healthiest sperm for assisted reproductive technologies,” Asghar noted.

The most commonly used or conventional method for assisted reproductive technologies involves a technique called centrifugation.

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Although this method is efficient at selecting motile and morphologically normal sperm, the process is problematic because it tends to increase levels of certain chemicals that cause DNA damage.

Asghar’s device consists of one inlet for the injection of a raw unprocessed semen sample and two plastic chambers separated by porous membrane.

Compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.

The findings were presented in the journal Biotechnology Advances.

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Health

HOTC sees remarkable success rate on kidney transplant

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HOTC sees remarkable success rate on kidney transplant

BHAKTAPUR — Shahid Dharmabhakta National Human Organ Transplant Centre (HOTC), Bhaktapur has successfully undertaken transplant of over 400 kidneys.

Hospital’s Executive Director Dr Pukar Chandra Shrestha, at a press conference organised here on Friday, informed that the Centre has so far successfully transplanted kidneys on 404 patients.

The Centre had initiated the kidney transplant service on January 19, 2013.

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The inflow of patients has alarmingly increased at the facility with the start of additional medical services such as urology, gastro surgery, cardio therapy, stone removal surgery along with other surgeries, besides kidney transplant, said Prof Dr Rakesh Verma.

However, the patients are compelled to wait for the transplant for long due to limited building space and availability of beds.

Right now, around 400 patients are waiting their turns for kidney transplant and more than this number are waiting to avail of dialysis service.

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