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9 in 10 cancers caused by lifestyle, not genes

Gorkha Post

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NEW YORK — A new study has claimed that an environmental and external factors, such as, smoking, drinking, sun and air pollution may account for up to nine out of 10 cancers.

It was earlier believed that irregular cell mutations played a significant role in the development of tumors, researchers said.

However, scientists at the Stony Brook University in New York now believe that outside influences have a far greater impact, meaning many cancers may be more preventable than previously thought.

According to the new research, nearly 75 per cent of the risk of colorectal cancer is now believed to be due to diet.

As many as 86 per cent of the risk of skin cancer is dueto sun exposure while 75 per cent of chance of developing head and neck cancers is because of tobacco and alcohol, researchers said.

The researchers said that cancer incidence is far too high to be explained away by simple mutations in cell division, ‘The Telegraph’ reported.

“Here we provide evidence that intrinsic risk factors contribute only modestly to cancer development. The rates of mutation accumulation by intrinsic processes are not sufficient to account for the observed cancer risks,” said Yusuf Hannun of Stony Brook University.

The researchers looked at previous studies which have shown how immigrants moving from low cancer incidence to countries with high cancer incidence soon develop the same tumour rates, suggesting the risks are environmental rather than biological or genetic.

“For many common types of cancer, this study concludes that at least 70 percent to 90 percent of the cancers are due to external risk factors roughly speaking, that 70 percent to 90 percent would not occur if we could magic away all the risk factors,” said Kevin McConway from the Open University in the UK.

Although some rare cancers can be driven by genetic mutations, the most prevalent diseases are down to environmental factors, researchers said, adding that it is important that these ‘extrinsic’ factors are taken into account in cancer prevention and research.

The finding is likely to prove controversial as it suggests that people could slash their risk of ever getting cancer if they just made lifestyle changes such as keeping out of the sun, exercising or cutting down on cigarettes, researchers said.

The findings were published in the journal Nature.

PTI

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Two died and eight injured in accident

Pratigya Waiju

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KATHMANDU—Today morning, Two died and eight injured when the microbus (Ba 3 Kha 4042) and minibus (Lu 1 Kha 4194)   collided each other in Myagade Rural Municipality-4 of Tanahu district.

Police has identified the deceased as Chija Kumari Batas of 50 and Saraswati Kunawar of 35.

The injured passengers of Microbus are identified as microbus driver Tul Bahadur BK, Sabila Khan Namuk Miya, Chandra Bhandari, Bindu Maya Thapa, Kamala Sura and Satyakala Neupane.

The cause of the accident is not identified yet.

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